Runa Berg Østby

• Stenseth, Else Berit; Østby, Runa Berg; Ersvær, Elisabeth; Kjøbli, Eli; Kvissel, Anne Katrine & Møller, Ina [Vis alle 8 forfattere av denne artikkelen] (2026). Praksisveiledning: Bruk av case i ekstern praksis. Bioingeniøren. ISSN 0801-6828. 1, s. 22–27. doi: https:/forskning.bioingenioren.no/originalartikkel/praksisveiledning-bruk-av-case-i-ekstern-praksis/144939. Fulltekst i vitenarkiv Vis sammendrag

  Innledning: Studien undersøker bruken av casebasert læring som en metode i praksisveiledning. Case er definert som bioingeniørfaglig relevante scenarioer brukt i teoretisk eller praktisk veiledning. Studien hadde som mål å kartlegge i hvilken grad case brukes i ekstern praksis, hvordan de utarbeides og anvendes på tvers av fagområder og læringssituasjoner, samt å kartlegge praksisveiledernes syn på fordeler og ulemper ved bruk av case. Metode: En deskriptiv metode med både kvantitative og kvalitative tilnærminger ble benyttet. Metoden er basert på en spørreundersøkelse sendt til praksisveiledere i norske sykehus i perioden juni 2023 til januar 2024. Det var totalt 51 respondenter. Resultat: Studien viser at 55 % av praksisveilederne som svarte på spørreundersøkelsen bruker case i veiledningen. Casene er hovedsakelig selvutviklede og basert på problemstillinger fra laboratoriehverdagen. Fra veiledernes perspektiv fremmer casebasert læring studentenes kritiske tenkning, selvstendighet og evne til å integrere teori og praksis. Blant veiledere som i dag ikke benytter case, uttrykte mange interesse for å implementere case i veiledningsarbeidet, samt å samarbeide med kolleger om å utvikle slike caser. Konklusjon: Studien fremhever potensialet casebasert læring har til å gjøre praksisperioden mer engasjerende, fremme dybdelæring og til å kunne tilpasses til studentenes individuelle behov.

• Nagy, Nina Elisabeth; Norli, Hans Ragnar; Fongen, Monica; Østby, Runa Berg; Heldal, Inger & Davik, Jahn [Vis alle 7 forfattere av denne artikkelen] (2022). Patterns and roles of lignan and terpenoid accumulation in the reaction zone compartmentalizing pathogen-infected heartwood of Norway spruce. Planta. ISSN 0032-0935. 255(3). doi: 10.1007/s00425-022-03842-1. Fulltekst i vitenarkiv Vis sammendrag

  Tree defense against xylem pathogens involves both constitutive and induced phenylpropanoids and terpenoids. The induced defenses include compartmentalization of compromised wood with a reaction zone (RZ) characterized by polyphenol deposition, whereas the role of terpenoids has remained poorly understood. To further elucidate the tree–pathogen interaction, we profiled spatial patterns in lignan (low-molecular-weight polyphenols) and terpenoid content in Norway spruce (Picea abies) trees showing heartwood colonization by the pathogenic white-rot fungus Heterobasidion parviporum. There was pronounced variation in the amount and composition of lignans between different xylem tissue zones of diseased and healthy trees. Intact RZ at basal stem regions, where colonization is the oldest, showed the highest level and diversity of these compounds. The antioxidant properties of lignans obviously hinder oxidative degradation of wood: RZ with lignans removed by extraction showed significantly higher mass loss than unextracted RZ when subjected to Fenton degradation. The reduced diversity and amount of lignans in pathogen-compromised RZ and decaying heartwood in comparison to intact RZ and healthy heartwood suggest that α-conindendrin isomer is an intermediate metabolite in lignan decomposition by H. parviporum. Diterpenes and diterpene alcohols constituted above 90% of the terpenes detected in sapwood of healthy and diseased trees. A significant finding was that traumatic resin canals, predominated by monoterpenes, were commonly associated with RZ. The findings clarify the roles and fate of lignan during wood decay and raise questions about the potential roles of terpenoids in signal transduction, synthesis, and translocation of defense compounds upon wood compartmentalization against decay fungi.

• Østby, Runa Berg; Didriksen, Terje; Antonsen, Simen Gjelseth; Nicolaisen, Steinar Sollien & Stenstrøm, Yngve H. (2020). Two-phase dibromocyclopropanation of unsaturated alcohols using flow chemistry. Molecules. ISSN 1431-5157. 25(10). doi: 10.3390/molecules25102364. Fulltekst i vitenarkiv Vis sammendrag

  Dibromocyclopropanations are conventionally done by addition of dibromocarbene to alkenes under phase-transfer conditions in batch reactions using a strong base (50% NaOH (aq)), vigorous stirring and long reaction times. We have shown that cyclopropanation of unsaturated alcohols can be done under ambient conditions using continuous flow chemistry with 40% (w/w) NaOH (aq) as the base. The reactions were generally rapid; the yields were comparable to yields reported in the literature for the conventional batch reaction

• Østby, Runa Berg; Stenstrøm, Yngve H. & Didriksen, Terje (2015). The use of flow chemistry for two-phase dibromocyclopropanation of alkenes. Journal of Flow Chemistry. ISSN 2062-249X. 5(2), s. 69–73. doi: 10.1556/JFC-D-14-00041. Fulltekst i vitenarkiv Vis sammendrag

  Conventional batch dibromocyclopropanations by reaction of bromoform and alkenes under phase-transfer conditions require strong base (50% NaOH (aq)), vigorous stirring, and often long reaction times. Using flow chemistry in a microreactor, the reactions were found to be smooth, rapid, and high-yielding under ambient conditions when 40% (w/w) NaOH was used as the base. The reaction has been tested with a representative selection of alkenes, displaying a variety of structural features.

• Østby, Runa Berg & Stenstrøm, Yngve (2014). Syntheses of bicyclo[3.3.0]octanes and bicyclo[4.3.0]nonanes by ring expansion of isopropylidenecyclobutanes. ARKIVOC. ISSN 1551-7004. s. 266–284. doi: 10.3998/ark.5550190.p008.383. Fulltekst i vitenarkiv Vis sammendrag

  When subjected to HBr/HOAc in polar solvents like acetic acid, 6-(1-methylethylidene)- bicyclo[3.2.0]heptanes undergo a ring expansion reaction yielding 2-bromo-3,3- dimethylbicyclo[3.3.0]octane and 3-bromo-2,2-dimethylbicyclo[3.3.0]octane. Several other isopropylidenecyclobutanes have been found to undergo the same reaction with high stereoselectivity and moderate regioselectivity. In less polar solvents like diethyl ether the ring expansion reaction is suppressed, and bromides resulting from addition of HBr to the isopropylidene double bond are obtained.

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• Antonsen, Simen Gjelseth; Østby, Runa Berg & Stenstrøm, Yngve H. (2018). Naturally Occurring Cyclobutanes, their Biological Significance and Synthesis. Elsevier. ISBN 9780444640574. 41 s. Fulltekst i vitenarkiv

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• Ersvær, Elisabeth; Stenseth, Else Berit; Kjøbli, Eli; Møller, Ina; Østby, Runa Berg & Solli, Ann Iren [Vis alle 16 forfattere av denne artikkelen] (2024). CaseMedLab - Caser og digitale læringsressurser innen laboratoriemedisin. Fulltekst i vitenarkiv Vis sammendrag

  Caser og digitale læringsressurser innen laboratoriemedisin

• Stenseth, Else Berit; Kvissel, Anne Katrine; Kjøbli, Eli; Lie-Jensen, Anette Christensen; Østby, Runa Berg & Jacobsen, Bente Marie Berntsen [Vis alle 9 forfattere av denne artikkelen] (2023). Bridging the Gap between working life and BLS education programs. Fulltekst i vitenarkiv
• Østby, Runa Berg; Didriksen, Terje; Antonsen, Simen Gjelseth; Nolsøe, Jens Mortansson Jelstrup; Stenstrøm, Yngve H. & Monsen, Erling Berge (2019). Two-phase Dibromocyclopropanation of Unsaturated Alcohols Using Flow Chemistry. Fulltekst i vitenarkiv
• Østby, Runa Berg; Antonsen, Simen Gjelseth; Stenstrøm, Yngve & Westerås, Stephen (2015). Synthesis of cyclobutanes by microwave assisted [2+2] intramolecular allene-ene reactions. Fulltekst i vitenarkiv
• Stenstrøm, Yngve H.; Hansen, Trond Vidar & Østby, Runa Berg (2015). Syntheses of 3-, 4- and 5-Membered Carbocycles - New Methodology on Old Methods. SiÅs, NMBU,Ås. ISSN 9788257513290. Fulltekst i vitenarkiv

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